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Drs. Ricardo Izurieta and Ligia Maria Cruz Espinoza and doctoral student Sharad Suryakant Malavade publish paper on Control of Soil Transmitted Helminthes

| Global Health, Monday Letter, Our Alumni, Our Research

Public health researchers published a paper on environmental control of geo-helminthes in the Health and the Environment Journal. Ricardo Izurieta, MD, DrPH,MPH, Ligia Maria Cruz Espinoza, PhD, and Sharad Suryakant Malavade, MPH,  authored the paper titled “A Novel Strategy for Environmental Control of Soil Transmitted Helminthes.”

Funded by the University of South Florida College of Public Health, the team’s research was successfully accomplished in collaboration with the Ministry of Health, El Salvador and the Pan American Health Organization (PAHO).

The Department of Global Health is the academic home for Drs. Izurieta, Cruz Espinoza and Mr. Malavade. Dr. Izurieta is an associate professor in the department. Dr. Cruz Espinoza earned a doctor of philosophy in global health. Sharad Suryakant Malavade holds a master of public health degree from the USF College of Public Health and is currently earning a doctorate in global health.

A video capsule of the project is available on the website of the Ministry of Health, El Salvador. This has been broadcasted in all Central American countries.  Visit the websites listed below to view the video capsules.

A Novel Strategy for Environmental Control of Soil Transmitted Helminthes

Sharad SMa, b*, Ligia Maria CEa and Ricardo Ia, b
a Dept. of Global Health, University of South Florida
b Donald Price Center for Parasite Repository and Education, University of South Florida
*Corresponding author email:
Published: 1 December 2012
ABSTRACT: Soil transmitted helminthes (STH) are important neglected tropical diseases widespread in developing countries. Repeated administration of anti-helminthics to adults and children for treatment and prevention of reinfection is frequently needed. The study aims to determine the effectiveness of urea for the inactivation of Ascaris suum eggs in the feces collection chamber of dry toilets in a tropical developing country. Sixty samples of approximately 10,000 Ascaris suum eggs each were randomly distributed equally in two groups; urea treatment and urea non-treatment. The treatment group toilets had urea added to the feces. The eggs were harvested at days 1,2,3,4 and 5 and then processed for assessment of viability by incubation in 0.1N sulphuric acid for three weeks. Viability was confirmed by observation of the larval form inside the egg by microscopy. Parameters like duration of treatment, concentration of gaseous ammonia generated, peak temperature achieved and change in moisture level were assessed utilizing multiple linear regression. Duration of treatment for at least 72 h (p<0.001; α=0.05) and gaseous ammonia concentrations of at least 109.5 ppm (p<0.001; α=0.05) were found to have a statistically significant association with at least 50% inactivation rate for the Ascaris suum eggs in 33% of the samples. Moisture level change and the peak temperature did not show any statistically significant effect on the inactivation of Ascaris suum eggs in our study. Urea is a potential field agent for the inactivation of geohelminth eggs for environmental control of soil transmitted helminthes through treatment of feces.