FEATURED PUBLICATIONS

All online and print featured publications below are selected by the USF Health Morsani College of Medicine Office of Research:

Bertalovitz AC, Osterbur Badhey ML, McDonald TV. Synonymous nucleotide modification of the KCNH2 gene affects both mRNA characteristics and translation of the encoded hERG ion channel. J Biol Chem. 2018 Jun 15. pii: jbc.RA118.001805. doi: 10.1074/jbc.RA118.001805. [Epub ahead of print] PubMed PMID: 29907571.

Kabir AU, Lee TJ, Pan H, Berry JC, Krchma K, Wu J, Liu F, Kang HK, Hinman K, Yang L, Hamilton S, Zhou Q, Veis DJ, Mecham RP, Wickline SA, Miller MJ, Choi K. Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis. JCI Insight. 2018 Apr 19;3(8). pii: 97349. doi: 10.1172/jci.insight.97349. [Epub ahead of print] PubMed PMID: 29669933; PubMed Central PMCID: PMC5931123.

Gupta N, Lee HS, Ryu JH, Taveira-DaSilva AM, Beck GJ, Lee JC, McCarthy K,Finlay GA, Brown KK, Ruoss SJ, Avila NA, Moss J, McCormack FX; NHLBI LAM Registry Group. The NHLBI LAM Registry: Prognostic physiological and radiological biomarkers emerge from a 15-year prospective longitudinal analysis. Chest. 2018 Jun 22. pii: S0012-3692(18)30934-6. doi: 10.1016/j.chest.2018.06.016. [Epub ahead of print] PubMed PMID: 29940164.

Tosur M, Geyer SM, Rodriguez H, Libman I, Baidal DA, Redondo MJ; Type 1 Diabetes TrialNet Study Group. Ethnic differences in progression of islet autoimmunity and type 1 diabetes in relatives at risk. Diabetologia. 2018 Jun 21. doi: 10.1007/s00125-018-4660-9. [Epub ahead of print] PubMed PMID: 29931415.

Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Alignment of Parent-and Child-Reported Outcomes and Histology in Eosinophilic Esophagitis Across Multiple CEGIR Sites. J Allergy Clin Immunol. 2018 May 28. pii: S0091-6749(18)30774-7. doi: 10.1016/j.jaci.2018.05.014. [Epub ahead of print] PubMed PMID: 29852258.

Singh P, Mahmoud R, Gold JA, Miller JL, Roof E, Tamura R, Dykens E, Butler MG, Driscoll DJ, Kimonis V. Multicentre study of maternal and neonatal outcomes in individuals with Prader-Willi syndrome. J Med Genet. 2018 May 18. pii: jmedgenet-2017-105118. doi: 10.1136/jmedgenet-2017-105118. [Epub ahead of print] PubMed PMID: 29776967.

 La Frazia S, Piacentini S, Riccio A, Rossignol JF, Santoro MG. The second-generation thiazolide haloxanide is a potent inhibitor of avian influenza virus replication. Antiviral Res. 2018 Jun 13. pii: S0166-3542(18)30079-2. doi: 10.1016/j.antiviral.2018.06.008. [Epub ahead of print] PubMed PMID: 29908209.

Li Z, Morano JP, Khoshnood K, Hsieh E, Sheng Y. HIV-related stigma among people living with HIV/AIDS in rural Central China. BMC Health Serv Res. 2018 Jun 15;18(1):453. doi: 10.1186/s12913-018-3245-0. PubMed PMID: 29903006.

Zeitler K, Jariwala R, Restrepo-Jaramillo R, Kapadia S, Casanas B, Alrabaa S, Sriaroon C. Successful use of subcutaneous ivermectin for the treatment of Strongyloides stercoralis hyperinfection in the setting of small bowel obstruction and paralytic ileus in the immunocompromised population. BMJ Case Rep. 2018 Jun 4;2018. pii: bcr-2017-223138. doi: 10.1136/bcr-2017-223138. PubMed PMID: 29866667; PubMed Central PMCID: PMC5990086.

Kim R, Coppola D, Wang E, Chang YD, Kim Y, Anaya D, Kim DW. Prognostic value of CD8CD45RO tumor infiltrating lymphocytes in patients with extrahepatic cholangiocarcinoma. Oncotarget. 2018 May 4;9(34):23366-23372. doi: 10.18632/oncotarget.25163. eCollection 2018 May 4. PubMed PMID: 29805739; PubMed Central PMCID: PMC5955104.

Zaman S, Chobrutskiy BI, Patel JS, Callahan BM, Tong WL, Blanck G. Mutant cytoskeletal and ECM peptides sensitive to the ST14 protease are associated with a worse outcome for glioblastoma multiforme. Biochem Biophys Res Commun. 2018 Jun 25. pii: S0006-291X(18)31454-2. doi: 10.1016/j.bbrc.2018.06.141. [Epub ahead of print] PubMed PMID: 29953855.

Poulsen SB, Marin De Evsikova C, Murali SK, Praetorius J, Chern Y, Fenton RA, Rieg T. Adenylyl cyclase 6 is required for maintaining acid-base homeostasis. Clin Sci (Lond). 2018 Jun 25. pii: CS20180060. doi: 10.1042/CS20180060. [Epub ahead of print] PubMed PMID: 29941522.

Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ. Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD. ACS Chem Biol. 2018 Jun 19. doi: 10.1021/acschembio.8b00454. [Epub ahead of print] PubMed PMID: 29893552.

Wang Y, Wang S, Kelly CP, Feng H, Greenberg A, Sun X. TPL2 is a key regulator of intestinal inflammation in C. difficile infection. Infect Immun. 2018 May 29. pii: IAI.00095-18. doi: 10.1128/IAI.00095-18. [Epub ahead of print] PubMed PMID: 29844241.

Pemberton OA, Zhang X, Nichols DA, DeFrees K, Jaishankar P, Bonnet R, Adams J, Shaw LN, Renslo AR, Chen Y. Antibacterial spectrum of a tetrazole-based reversible inhibitor of serine β-lactamases. Antimicrob Agents Chemother. 2018 May 29. pii: AAC.02563-17. doi: 10.1128/AAC.02563-17. [Epub ahead of print] PubMed PMID: 29844038.

Tikhonova TN, Rovnyagina NR, Zherebker AY, Sluchanko NN, Rubekina AA, Orekhov AS, Nikolaev EN, Fadeev VV, Uversky VN, Shirshin EA. Dissection of the deep-blue autofluorescence changes accompanying amyloid fibrillation. Arch Biochem Biophys. 2018 Aug 1;651:13-20. doi: 10.1016/j.abb.2018.05.019. Epub 2018 May 24. PubMed PMID: 29803394.

Askenasy I, Murray DT, Andrews RM, Uversky VN, He H, Stroupe ME. Structure-Function Relationships in the Oligomeric NADPH-Dependent Assimilatory Sulfite Reductase. Biochemistry. 2018 Jun 4. doi: 10.1021/acs.biochem.8b00446. [Epub ahead of print] PubMed PMID: 29787249.

Falasiri S, Rahman T, Tu YN, Fawcett TJ, Blanck G. Germline cytoskeletal and extra-cellular matrix-related single nucleotide variations associated with distinct cancer survival rates. Gene. 2018 Aug 30;669:91-98. doi: 10.1016/j.gene.2018.05.037. Epub 2018 May 17. PubMed PMID: 29778426.

Delic V, Kurien C, Cruz J, Zivkovic S, Barretta J, Thomson A, Hennessey D, Joseph J, Ehrhart J, Willing AE, Bradshaw P, Garbuzova-Davis S. Discrete mitochondrial aberrations in the spinal cord of sporadic ALS patients. J Neurosci Res. 2018 Aug;96(8):1353-1366. doi: 10.1002/jnr.24249. Epub 2018 May 6. PubMed PMID: 29732581.

Mok SA, Condello C, Freilich R, Gillies A, Arhar T, Oroz J, Kadavath H, Julien O, Assimon VA, Rauch JN, Dunyak BM, Lee J, Tsai FTF, Wilson MR, Zweckstetter M, Dickey CA, Gestwicki JE. Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nat Struct Mol Biol. 2018 May;25(5):384-393. doi: 10.1038/s41594-018-0057-1. Epub 2018 Apr 30. PubMed PMID: 29728653; PubMed Central PMCID: PMC5942583.

Kim MY, Kim JS, Son SH, Lim CS, Eum HY, Ha DH, Park MA, Baek EJ, Ryu BY, Kang HC, Uversky VN, Kim CG. Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis. Nucleic Acids Res. 2018 Jun 1;46(10):4933-4949. doi: 10.1093/nar/gky193. PubMed PMID: 29547954.

Patel D, Xu C, Nagarajan S, Liu Z, Hemphill WO, Shi R, Uversky VN, Caldwell GA, Caldwell KA, Witt SN. Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson’s disease. Hum Mol Genet. 2018 May 1;27(9):1514-1532. doi: 10.1093/hmg/ddy059. PubMed PMID: 29452354.

Yang X, Meegan JE, Jannaway M, Coleman DC, Yuan SY. A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation. Cardiovasc Res. 2018 Jun 23. doi: 10.1093/cvr/cvy167. [Epub ahead of print] PubMed PMID: 29939250.

Zhang S, Huang Q, Wang Q, Wang Q, Cao X, Zhao L, Xu N, Zhuge Z, Mao J, Fu X, Liu R, Wilcox CS, Patzak A, Li L, Lai EY. Enhanced Renal Afferent Arteriolar Reactive Oxygen Species and Contractility to Endothelin-1 Are Associated with Canonical Wnt Signaling in Diabetic Mice. Kidney Blood Press Res. 2018;43(3):860-871. doi: 10.1159/000490334. Epub 2018 May 30. PubMed PMID: 29870994.

Zhang G, Wang Q, Wang W, Yu M, Zhang S, Xu N, Zhou S, Cao X, Fu X, Ma Z, Liu R, Mao J, Lai EY. Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity. Kidney Blood Press Res. 2018;43(3):904-913. doi: 10.1159/000490338. Epub 2018 May 30. PubMed PMID: 29870982.

Baghdadi MB, Castel D, Machado L, Fukada SI, Birk DE, Relaix F, Tajbakhsh S, Mourikis P. Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche. Nature. 2018 May;557(7707):714-718. doi: 10.1038/s41586-018-0144-9. Epub 2018 May 23. PubMed PMID: 29795344; PubMed Central PMCID: PMC5985950.

Wang L, Wang X, Jiang S, Wei J, Buggs J, Fu L, Zhang J, Liu R. Graft function assessment in mouse models of single- and dual- kidney transplantation. Am J Physiol Renal Physiol. 2018 May 23. doi: 10.1152/ajprenal.00068.2018. [Epub ahead of print] PubMed PMID: 29790388.

Stanford KR, Taylor-Clark TE. Mitochondrial modulation-induced activation of vagal sensory neuronal subsets by antimycin A, but not CCCP or rotenone, correlates with mitochondrial superoxide production. PLoS One. 2018 May 7;13(5):e0197106. doi: 10.1371/journal.pone.0197106. eCollection 2018. PubMed PMID: 29734380; PubMed Central PMCID: PMC5937758.

Hasan TF, Duarte W, Akinduro OO, Goldstein ED, Hurst R, Haranhalli N, Miller DA, Wharen RE Jr, Tawk RG, Freeman WD. Nonaneurysmal “Pseudo-Subarachnoid Hemorrhage” Computed Tomography Patterns: Challenges in an Acute Decision-Making Heuristics. J Stroke Cerebrovasc Dis. 2018 Jun 5. pii: S1052-3057(18)30192-7. doi: 10.1016/j.jstrokecerebrovasdis.2018.04.016. [Epub ahead of print] PubMed PMID: 29884521.

Dela Peña IC, Yang S, Shen G, Fang Liang H, Solak S, Borlongan CV. Extension of Tissue Plasminogen Activator Treatment Window by Granulocyte-Colony Stimulating Factor in a Thromboembolic Rat Model of Stroke. Int J Mol Sci. 2018 May 31;19(6). pii: E1635. doi: 10.3390/ijms19061635. PubMed PMID: 29857523.

Borlongan CV. Fatty acid chemical mediator provides insights into the pathology and treatment of Parkinson’s disease. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6322-6324. doi: 10.1073/pnas.1807276115. Epub 2018 May 30. PubMed  PMID: 29848628; PubMed Central PMCID: PMC6016787.

Schoenberg MR, Clifton WE, Sever RW, Vale FL. Neuropsychology Outcomes Following Trephine Epilepsy Surgery: The Inferior Temporal Gyrus Approach for Amygdalohippocampectomy in Medically Refractory Mesial Temporal Lobe Epilepsy. Neurosurgery. 2018 Jun 1;82(6):833-841. doi: 10.1093/neuros/nyx302. PubMed PMID: 28595352; PubMed Central PMCID: PMC5952931.

Sinkey RG, Lacevic J, Reljic T, Hozo I, Gibson KS, Odibo AO, Djulbegovic B, Lockwood CJ. Elective induction of labor at 39 weeks among nulliparous women: The impact on maternal and neonatal risk. PLoS One. 2018 Apr 25;13(4):e0193169. doi: 10.1371/journal.pone.0193169. eCollection 2018. PubMed PMID: 29694344; PubMed Central PMCID: PMC5918610.

Odibo AO, Nwabuobi C, Odibo L, Leavitt K, Obican S, Tuuli MG. Customized fetal growth standard compared to the Intergrowth-21st Century standard at predicting small-for gestational age neonates. Acta Obstet Gynecol Scand. 2018 Jun 7. doi: 10.1111/aogs.13394. [Epub ahead of print] PubMed PMID: 29878301.

Mong EF, Akat KM, Canfield J, Lockhart J, VanWye J, Matar A, Tsibris JCM, Wu JK, Tuschl T, Totary-Jain H. Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution. Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):1321-1332. doi: 10.1161/ATVBAHA.118.310908. Epub 2018 May 3. PubMed PMID: 29724816; PubMed Central PMCID: PMC5970092.

Devulapalli KK, Fidelman N, Soulen MC, Miller M, Johnson MS, Addo E, El-Haddad G, Nutting C, Morrison J, Farsad K, Lokken RP, Gaba RC, Fleming J, Brown DB, Kwan SW, Rose SC, Pennycooke KA, Liu DM, White SB, Gandhi R, Lazar AA, Kerlan RK Jr. (90)Y Radioembolization for Hepatic Malignancy in Patients with Previous Biliary Intervention: Multicenter Analysis of Hepatobiliary Infections. Radiology. 2018 May 8:170962. doi: 10.1148/radiol.2018170962. [Epub ahead of print] PubMed PMID: 29737954.

Neill KG, Saller J, Al Diffalha S, Centeno BA, Malafa MP, Coppola D. EGFR L861Q Mutation in a Metastatic Solid-pseudopapillary Neoplasm of the Pancreas. Cancer Genomics Proteomics. 2018 May-Jun;15(3):201-205. PubMed PMID: 29695402; PubMed Central PMCID: PMC5971012.

Leyngold I, Weller C, Leyngold M, Espana E, Black KD, Hall KL, Tabor M. Endoscopic Corneal Neurotization: Cadaver Feasibility Study. Ophthalmic Plast Reconstr Surg. 2018 May/Jun;34(3):213-216. doi: 10.1097/IOP.0000000000000913. PubMed PMID: 28472009.

Donohue DM, Santoni BG, Stoops TK, Tanner G, Diaz MA, Mighell M. Biomechanical Comparison of 3 Inferiorly Directed Versus 3 Superiorly Directed Locking Screws on Stability in a 3-Part Proximal Humerus Fracture Model. J Orthop Trauma. 2018 Jun;32(6):306-312. doi: 10.1097/BOT.0000000000001112. PubMed PMID: 29401089.

Leigh BA, Breitbart M, Oksanen HM, Bamford DH, Dishaw LJ. Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta. Genome Announc. 2018 May 24;6(21). pii: e00368-18. doi: 10.1128/genomeA.00368-18. PubMed PMID: 29798916; PubMed Central PMCID: PMC5968719.

Tirosh I, Yamazaki Y, Frugoni F, Ververs FA, Allenspach EJ, Zhang Y, Burns S, Al-Herz W, Noroski L, Walter JE, Gennery AR, van der Burg M, Notarangelo LD, Lee YN. Recombination activity of human recombination-activating gene 2 (RAG2) mutations and correlation with clinical phenotype. J Allergy Clin Immunol. 2018 Jun 16. pii: S0091-6749(18)30699-7. doi: 10.1016/j.jaci.2018.04.027. [Epub ahead of print] PubMed PMID: 29772310.

Jilling T, Ambalavanan N, Cotten CM, Martin CA, Maheshwari A, Schibler K, Levy J, Page GP. Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. Pediatr Res. 2018 May;83(5):943-953. doi: 10.1038/pr.2018.33. Epub 2018 May 16. PubMed PMID: 29538362.

Huber KM, Clayman E, Kumar A, Smith P. The Impact of Perioperative Hormonal Therapy for Breast Cancer on Transverse Rectus Abdominis Myocutaneous Flap Abdominal Complications. Ann Plast Surg. 2018 Jun;80(6S Suppl 6):S348-S351. doi: 10.1097/SAP.0000000000001323. PubMed PMID: 29369111.

Cozart B, Diaz Vera J, Denham JD, Whiting WL. Treatment of Depression With Duloxetine in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes. Clin Neuropharmacol. 2018 May/Jun;41(3):103-105. doi: 10.1097/WNF.0000000000000277. PubMed PMID: 29596118.

Dismuke-Greer CE, Nolen TL, Nowak K, Hirsch S, Pogoda TK, Agyemang AA, Carlson KF, Belanger HG, Kenney K, Troyanskaya M, Walker WC. Understanding the impact of mild traumatic brain injury on veteran service-connected disability: results from Chronic Effects of Neurotrauma Consortium. Brain Inj. 2018 Jun 11:1-10. doi: 10.1080/02699052.2018.1482428. [Epub ahead of print] PubMed PMID: 29889561.

Silva MA, Belanger HG, Dams-O’Connor K, Tang X, McKenzie-Hartman T, Nakase-Richardson R. Prevalence and predictors of tobacco smoking in veterans and service members following traumatic brain injury rehabilitation: a VA TBIMS study. Brain Inj. 2018;32(8):994-999. doi: 10.1080/02699052.2018.1468576. Epub 2018 Apr 30. PubMed PMID: 29708447.

Chung KK, Coates EC, Hickerson WL, Arnold-Ross AL, Caruso DM, Albrecht M, Arnoldo BD, Howard C, Johnson LS, McLawhorn MM, Friedman B, Sprague AM, Mosier MJ, Conrad PF, Smith DJ Jr, Karlnoski RA, Aden JK, Mann-Salinas EA, Wolf SE; Randomized controlled Evaluation of high-volume hemofiltration in adult burn patients with Septic shoCk and acUte kidnEy injury (RESCUE) Investigators. Renal Replacement Therapy in Severe Burns: A Multicenter Observational Study. J Burn Care Res. 2018 Jun 20. doi: 10.1093/jbcr/iry036. [Epub ahead of print] PubMed PMID: 29931223.

Veronesi G, Park B, Cerfolio R, Dylewski M, Toker A, Fontaine JP, Hanna WC, Morenghi E, Novellis P, Velez-Cubian FO, Amaral MH, Dieci E, Alloisio M, Toloza EM. Robotic resection of Stage III lung cancer: an international retrospective study. Eur J Cardiothorac Surg. 2018 Apr 30. doi: 10.1093/ejcts/ezy166. [Epub ahead of print] PubMed PMID: 29718155.

Patel DN, Feng T, Simon RM, Howard LE, Vidal AC, Moreira DM, Castro-Santamaria R, Roehrborn C, Andriole GL, Freedland SJ. PSA predicts development of incident lower urinary tract symptoms: results from the REDUCE study. Prostate Cancer Prostatic Dis. 2018 Jun;21(2):238-244. doi: 10.1038/s41391-018-0044-y. Epub 2018 May 23. PubMed PMID: 29795141.