Enzyme SSH1 impairs the disposal of accumulating cellular “garbage,” leading to brain cell death
University of South Florida Health neuroscientists discover a defect early in autophagy that may help develop SSH1 inhibitors to treat Alzheimer’s and other neurodegenerative diseases TAMPA, Fla (Oct. […]
Beta-arrestin2 increases neurotoxic tau driving frontotemporal dementia
University of South Florida study suggests a new approach to inhibit the buildup of brain-damaging tau tangles associated with FTLD, Alzheimer’s disease and related dementias TAMPA, Fla. (Feb. […]
David Kang probes brain changes in aging that tip the balance toward dementia
His team searches beyond the hallmark Alzheimer’s disease proteins for alternative treatments In his laboratory at the USF Health Byrd Alzheimer’s Center, neuroscientist David Kang, PhD, focuses on […]
Cofilin may be early culprit in tauopathy process leading to brain cell death
USF Health study links Aβ-activated enzyme cofilin with the toxic tau tangles in major neurodegenerative disorders like Alzheimer’s disease TAMPA, Fla. — The two primary hallmarks of Alzheimer’s […]
Research at USF Health reveals ALS and FTD gene link to pathology
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two rare neurodegenerative diseases also considered as spectrum disorders, affect thousands of Americans every year. ALS, a condition that effects […]
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