New study reveals strategy for creating COVID-19 drugs to dually inhibit the virus’s entry and replication
University of South Florida Health-University of Arizona team reports compounds simultaneously targeting Mpro and cathepsin L may improve treatment of COVID-19 infection TAMPA, Fla (Nov. 6, 2020) — […]
Compounds halt SARS-CoV-2 replication by targeting key viral enzyme
A University of Arizona-University of South Florida team identified and analyzed four promising antiviral drug candidates in the preclinical study TAMPA, Fla. (July 6, 2020) — As the […]
USF Health microbiologist shares team’s progress on vaccine for C. diff infection
A team led by Xingmin Sun, PhD, assistant professor in the USF Health Department of Molecular Medicine, is working on vaccine options for Clostridium difficile infection, or CDI, […]
USF neuroscientist probes how different states of tau drive brain cell damage
Research by Laura Blair’s team seeking to untangle tau may lead to targeted treatments for Alzheimer’s, Parkinson’s and other neurodegenerative diseases Both of USF Health neuroscientist Laura Blair’s grandmothers […]
Research at USF Health reveals ALS and FTD gene link to pathology
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two rare neurodegenerative diseases also considered as spectrum disorders, affect thousands of Americans every year. ALS, a condition that effects […]
Dr. Mack Wu studies molecular control of ischemia-reperfusion injury, leaky gut
USF Health researcher Mack Wu, MD, studies what happens when the microvascular endothelial barrier controlling blood-tissue exchange is compromised during ischemia-reperfusion injury, a condition that can lead to […]
A human enzyme can reduce neurotoxic amyloids in mouse model of dementia
The USF-led study suggests CyP40 or similar proteins may be potential therapeutics for Alzheimer’s and Parkinson’s diseases TAMPA, Fla. (June 27, 2017) — A naturally occurring human enzyme […]