Posts Tagged NIH

Compounds halt SARS-CoV-2 replication by targeting key viral enzyme

A University of Arizona-University of South Florida team  identified and analyzed four promising antiviral drug candidates in the preclinical study TAMPA, Fla. (July 6, 2020) — As the […]

USF Health team identifies mouse model to better study prevalent form of heart failure linked to age-related obesity

Mice deficient in a receptor needed to safely clear unresolved cardiac inflammation may help in discovering therapies for heart failure with preserved ejection fraction TAMPA, Fla (June 22, […]

Inhibiting thrombin protects against dangerous infant digestive disease

A USF Health-Johns Hopkins Medicine team shows that nanoparticles targeting the blood-clotting protein reduces necrotizing enterocolitis-like injury in neonatal mice TAMPA, Fla. (May 4, 2020) — Necrotizing enterocolitis […]

Distinct lipid biomarkers key to cardiac repair differences in blacks and whites after heart attack

USF Health-UAB study indicates that lipid mediators may offer new targets for more personalized heart failure diagnosis and treatment TAMPA, Fla (May 4, 2020) — Black men and […]

Beta-arrestin2 increases neurotoxic tau driving frontotemporal dementia

University of South Florida study suggests a new approach to inhibit the buildup of brain-damaging tau tangles associated with FTLD, Alzheimer’s disease and related dementias TAMPA, Fla. (Feb. […]

Gopal Thinakaran pursues genetic clues to Alzheimer’s disease pathways

The USF Health neurobiologist focuses on understanding genetic risk factors that may offer new therapy targets to delay or protect against age-related cognitive decline There has been a […]

New study identifies inflammatory molecules controlling capillary loss common in many diseases

Using an innovative cellular model, the USF Health-led study also discovers drug combinations to prevent degeneration of these tiniest blood vessels Many diseases arise from abnormalities in our […]

Brendan Walker studies brain changes driving addictive behaviors

The USF Health neuroscientist aims to translate his research on kappa opioid receptors into personalized treatments for alcoholism and other addictive disorders When USF Health neuroscientist Brendan Walker, […]

Black children respond differently to step-up asthma therapy

USF Health’s Dr. Juan Carlos Cardet was among the authors of a new multi-site clinical study reported in the New England Journal of Medicine Black children respond differently […]

Tiny cargo carriers rich in c-Src protein contribute to disease progression

New USF Health research on endothelial-derived microvesicles, using models of sepsis, may be useful for better diagnosis and treatment of inflammatory or infectious diseases A new preclinical study […]