Emergency -

University of South Florida

USF WHC & USF Health Office of Research Seed Grant Awarded: Guzeloglu-Kayisli Team

$20,000 to be funded July 1, 2015 – June 30, 2016

Therapeutic Induction of Progesterone Receptor B in Term Decidual Cells using Microspheres Technology

  • Ozlem Guzeloglu-Kayisli, MSc., PhD, Assistant Professor, Morsani College of Medicine
  • Yashwant Pathak, MPharm, EMBA, MS, PhD, Professor, College of Pharmacy
  • Vijaykumar Sutariya, MPharm, PhD, Assistant Professor, College of Pharmacy
  • Kirpal Bisht, PhD, Associate Professor, College of Arts & Sciences

Description:

Preterm birth (PTB) is the most frequent cause of neonatal death and the second leading cause of mortality worldwide. We purpose to develop a novel microspheres-mediated method to delivery of a progesterone receptor-expressing vector to term decidual cells for use as potential therapy in preventing inflammation-induced PTB.

 Kayisli